A REPORTER GENE ASSAY FOR IDENTIFYING A COMPOUND AS SELECTIVE INHIBITOR OF PDE10 SUBTYPE

摘要

The present invention provides a method for identifying a compound as selective inhibitor of PDE10 subtype employing luciferase based reporter gene assay. The method of the present invention provide a simple and sensitive assay for high throughput screening of compounds as selective inhibitor of PDE10 subtype for development of antipsychotic drugs for treatment of various neurological and psychiatric disorders.