首页> 外国专利> COMBINATION OF GLYCOISOFORMS FOR THE TREATMENT OR PREVENTION OF SEPTICEMIA, TRANSGENIC CELL LINE THAT PRODUCES ERYTHROPOIETIN GLYCOISOFORMS, PHARMACEUTICAL COMPOSITION COMPRISING SAID COMBINATION.

COMBINATION OF GLYCOISOFORMS FOR THE TREATMENT OR PREVENTION OF SEPTICEMIA, TRANSGENIC CELL LINE THAT PRODUCES ERYTHROPOIETIN GLYCOISOFORMS, PHARMACEUTICAL COMPOSITION COMPRISING SAID COMBINATION.

机译:用于治疗或预防癫痫症的糖异能体的组合,产生促红细胞生成素糖异能体的转基因细胞系,包含上述组合的药物组合物。

摘要

The invention relates to a combination of erythropoietin glycoisoforms, in which said glycoisoforms can comprise between 4 and 10 sialic acid molecules per molecule of erythropoietin. The aforementioned combination of glycoisoforms can be used for the treatment or prevention of septicemia/sepsis. The invention also relates to a pharmaceutical composition comprising the above-mentioned combination, a cell line that produces a combination of erythropoietin glycoisoforms, methods of obtaining the cell line, a method of producing the combination of glycoisoforms and methods for the treatment and prevention of septicemia/sepsis.
机译:本发明涉及促红细胞生成素糖同工型的组合,其中所述糖同工型每促红细胞生成素分子可包含4至10个唾液酸分子。糖异形体的上述组合可以用于治疗或预防败血病/败血症。本发明还涉及药物组合物,其包含上述组合,产生促红细胞生成素糖同工型的组合的细胞系,获得该细胞系的方法,生产糖同工型的组合的方法以及用于治疗和预防败血病的方法。 /败血症。

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