method of modulating the protein kinase system activated by stress

摘要

described are processes for the modulation of stress activated protein kinase (sapk) with an active compound.in which the active compound is a low power, at least for the inhibition of p38 mapk, and in which the contacting is conducted at a concentration of modulation of the sapk eis a low percentage inhibitory concentration for the inhibition of p38 mapk by the at least one compound. pirfenidone derivatives are also described.these derivatives can modulate a system of stress activated protein kinase (sapk).