首页> 外国专利> A new process for the preparation of epothilone derivatives, new epothilone derivatives as well as new intermediate products for the process and the methods of preparing same

A new process for the preparation of epothilone derivatives, new epothilone derivatives as well as new intermediate products for the process and the methods of preparing same

机译:制备埃坡霉素衍生物的新方法,新的埃坡霉素衍生物以及该方法的新中间体及其制备方法

摘要

Disclosed is a synthesis for the preparation of epothilone derivatives of formula (9) wherein R1 is methyl, and R2 has the meaning of an unsubstituted or substituted aryl, an unsubstituted or substituted heteroaryl or an unsubstituted or substituted heterocyclic radical fused to a benzene nucleus, and salts thereof, and intermediates for the synthesis of a compound of formula (9).
机译:公开了用于制备式(9)的埃坡霉素衍生物的合成方法,其中R 1是甲基,并且R 2具有未取代或取代的芳基,未取代或取代的杂芳基或与苯核稠合的未取代或取代的杂环基的含义,及其盐,以及用于合成式(9)化合物的中间体。

著录项

  • 公开/公告号NZ538612A

    专利类型

  • 公开/公告日2008-01-31

    原文格式PDF

  • 申请/专利权人 NOVARTIS AG;

    申请/专利号NZ20030538612

  • 发明设计人 KOCH GUIDO;LOISELEUR OLIVIER;

    申请日2003-09-12

  • 分类号C07D493/04;C07D303/14;C07D303/16;C07D275/06;A61P35/00;

  • 国家 NZ

  • 入库时间 2022-08-21 20:06:38

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