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Tricyclic n-heteromorphic carbohydrate derivatives containing residual benzene, their preparation and use in therapists
Tricyclic n-heteromorphic carbohydrate derivatives containing residual benzene, their preparation and use in therapists
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机译:含有残留苯的三环正杂型碳水化合物衍生物,其制备及在治疗师中的应用
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摘要
It refers to a formula compound, in which a is a monocyclic or monocyclic heterocyclic cycle, from concentration to other benzene 4-7 rings; P is a monocyclic or monocyclic heterocyclic cycle, consisting of 8-11 rings, consisting of 1-6 variants selected from O, s, N, R1 between H, halogen, oxo, uncle, C1-C6 asphalt and O, s; R2 is h, halogen, C1-C6, C1-C6, C3-C7, etc.; R3 is h, halogen, C1-C6, C3-C7, C1-C6, C1-C6, fluorine chlorine. The preferred compound is n - (1,2,3,4-tetrahydropyridine [1,2-a] benzo-7-il) - 5-fluoro-1 - [(pyridine-4-il) methyl] - 1h-indol-2-carboxamida;N - (2,3-dihydro-1h-pirrolo [1,2-a] biphenyl-6-il) - 5-fluoro-1 - [(piridin-4-il) methyl] - 1h-indol-2-carboxamida, etc. The preparatory process was also mentioned. These compounds are stimulants for the treatment of TRPV1 receptors in pain, inflammation, spinal cord and / or brain trauma, izmia, etc.
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