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Pyrethroid derivatives can activate respiratory tract as protein inhibitors
Pyrethroid derivatives can activate respiratory tract as protein inhibitors
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机译:拟除虫菊酯衍生物可以激活呼吸道作为蛋白质抑制剂
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摘要
It refers to a single ring compound with 5 to 12 members, in which J is arilo, heteroorganism, etc.; R1 is - (CR2) l-nr2, - (CR2) l-nrc (NR) - NR2, - (CR2) L-C (= NR) - NR2, or heterocycle with 5 to 7 members, R is h, asphalt (C1-C6),1. Aluminum (C2-C6) or asphalt (C2-C6);R2 is a tar (C1-C6),Alquenilo(C2-C6),Blue Nile (C2-C6),W is - O (CR2) k -,-S(CR2)K-,S (o) (CR2) k or OC (o) (CR2) k, where K and L are 0 to 6; R3 is nr7r8 or R6, where R7 and R8 are h, tar (C1-C6),Alquenilo(C2-C6),R4 and R5 are h, tar (C1-C6), among others,Alcoxi(C1-C6),R10 is, among other things, halogen, tar (C1-C6),Alcoxi et al; R6 and X are a 5 to 7 member carbon thyroid ring, a heterosexual, arilo or heterosexual ring; I is 0 or 1; m and N are 1 to 6; P are 0 to 3. The most popular compound is formula compound (II),(iii)There are others He also mentioned a composer of pharmacology These compounds are respiratory tract (CAP) protein inhibitors for the treatment of monomeric fibrosis, lung cancer, chronic bronchitis and asthma.
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