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COMPOUNDS HAVING PROLYL OLIGOPEPTIDASE INHIBITORY ACTIVITY

机译:具有脯氨酸寡肽酶抑制活性的化合物

摘要

The invention provides a compound of formula (I), wherein in the formula X, R1, R2 and R3 are as defined in claim 1, or a pharmaceutically acceptable salt or ester thereof, useful as a prolyl oligopeptidase inhibitor. The compounds of formula (I) can be used for the treatment of diseases or conditions where prolyl oligopeptidase inhibitors are indicated to be effective, for example for the treatment of neurodegenerative diseases, such as Alzheimer's disease and senile dementia.
机译:本发明提供了式(I)的化合物,其中式X中,R 1,R 2和R 3如权利要求1所定义,或其药学上可接受的盐或酯,可用作脯氨酰寡肽酶抑制剂。式(I)化合物可以用于治疗脯氨酰寡肽酶抑制剂被证明有效的疾病或病症,例如用于治疗神经退行性疾病,例如阿尔茨海默氏病和老年性痴呆。

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