SEQUENCES OF NUCLEOTIDES AND AMINO ACIDS OF THE VIRUS GB, GC AND GD OF THE CANINE HERPES AND ITS USES.

摘要

NUCLEOTIDES ARE PRESENTED AND REIVINDICATED FOR GENES THAT CODIFY THE GB, GC AND GD HOMOLOGIES OF HERPESVIRUS CANINOS (CHV). THESE GENES CODIFY THE AMINO ACIDS POLYPEPTIDES 879, 459 AND 345, RESPECTIVELY THAT THEY ALSO PRESENT AND REIVINDICATE. GENES ARE USEFUL AS DNA PROBES, OR TO PREPARE PCR INITIATING LOADS. POLYPEPTIDES ARE USEFUL IN ANTIGENIC AND IMMUNOLOGICAL COMPOUNDS AS WELL AS IN VACCINES. NUCLEOTIDES CAN BE EXPRESSED IN ANY PROPER VECTOR SYSTEM, ALLOWING THE PRODUCTION OF POLYPEPTIDES. ADDITIONALLY, THE VECTOR SYSTEM THAT CONTAINS ANY OR ANY COMBINATION OF THE NUCLEOTIDES MAY BE USED IN AN ANTIGENIC, IMMUNOLOGICAL OR VACCINE COMPOUND, AS A POXVIRUS VECTOR SYSTEM, P.E. A CHV VACCINE OR RECOMBINANT OF AVIPOX VIRUSES, AS WELL AS THE PRODUCTS OF ITS EXPRESSION SUCH AS GLUCOPROTEINS GB, GC AND GD. ANTIBODIES OBTAINED FROM GLUCOPROTEINS OR FROM THE EXPRESSION OF THE VECTOR CONTAINING THE NUCLEOTIDO-STAMBIEN ALSO HAVE USEFULNESS. THE METHODS TO MAKE AND USE THE COMPOUND ARE ALSO EXPOSED AND REIVINDICATED. THE GB, GC AND GD RECOMBINANTS OF CANARIPOX-CHV, VCP 320, VCP322 AND VCP294 ARE ALSO EXPOSED AND RECIVINED AS WELL AS METHODS TO MAKE AND USE THEM.