POTENTIAL OF THE IMMUNE RESPONSE FOR APPLICATIONS OF VACCINES AND GENETIC THERAPY.

摘要

An expression box, comprising a promoter operably linked to a nucleic acid molecule that, when transcribed in vivo, forms a double-stranded RNA that induces the production of interferon, in which the expression box is selected from the group consisting of: (a) an expression box that, when transcribed in vivo, forms self-complementary RNA; and (b) an expression box comprising a first promoter operably linked to a first nucleic acid molecule, and a second promoter operably linked to a second nucleic acid molecule, wherein the first and second molecules of Nucleic acid, when transcribed in vivo, forms a double-stranded RNA that induces the production of interferon.