AEROSOL FORMULATION FOR INHALATION, CONTAINING TIOTROPE BROMIDE.

摘要

Drug preparation which is composed of tiotropium bromide as an active substance, in a concentration, referred to tiotropium, between 0.02 g per 100 ml of formulation and 0.05 g per 100 ml of formulation, with tiotropium bromide dissolved by complete in the drug preparation, -water as the sole solvent, -acid to adjust a pH value between 2.7 and 3.1, preferably between 2.8 and 3.05, -benzalkonium chloride in a concentration between 8 mg / 100 ml and 12 mg / 100 ml of formulation, sodium sodium acetate in an amount between 8 mg / 100 ml and 12 mg / 100 ml of formulation.