首页> 外国专利> PROCEDURE FOR THE PRODUCTION OF L-LISINE OR L-TREONIN USING THE BACHTERIA ESCHERICHIA THAT PRESENTS ACTIVITY OF THE MALIC ENZYME ATTENED.

PROCEDURE FOR THE PRODUCTION OF L-LISINE OR L-TREONIN USING THE BACHTERIA ESCHERICHIA THAT PRESENTS ACTIVITY OF THE MALIC ENZYME ATTENED.

机译:使用呈现出所关注的苹果酵素的活性的大肠杆菌来生产L-赖氨酸或L-苏氨酸的方法。

摘要

Process for producing L-lysine or L-threonine, which comprises the cultivation of a bacterium in a medium to produce and secrete said L-lysine or L-threonine, and collect the L-lysine or L-threonine from the medium, in which said bacterium is an Escherichia bacterium that has the capacity to produce L-lysine or L-threonine, and in which said bacterium is modified so that a malic enzyme is eliminated or the activity of a malic enzyme is reduced compared to a non-strain modified, in which the gene encoding said malic acid enzyme comprises sfcA and / or b2463.
机译:生产L-赖氨酸或L-苏氨酸的方法,其包括在培养基中培养细菌以生产和分泌所述L-赖氨酸或L-苏氨酸,并从培养基中收集L-赖氨酸或L-苏氨酸。所述细菌是具有产生L-赖氨酸或L-苏氨酸的能力的埃希氏菌属细菌,并且其中所述细菌经修饰以与不经修饰的菌株相比,苹果酸酶被消除或苹果酸酶的活性降低。 ,其中编码所述苹果酸酶的基因包含sfcA和/或b2463。

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