A PROCESS FOR MAKING 2-(METHYLTHIO)-5-(TRIFLUOROMETHYL)-1,3,4-THIADIAZOLE USING METHYLDITHIOCARBAZINATE WITH TRIFLUOROACETIC ACID WITH SELECTIVE REMOVAL OF 2,5-BIS(METHYLTHIO)-1,3,4-THIADIAZOLE

摘要

The present invention provides a process for making 2- (methyithio)-5-(trifluoromethyl)-1,3,4-thiadiazole. The process includes the steps of reacting methyidithiocarbazinate with trifluoroacetic acid to form a mixture of 2-(methylthio)-5-(trifluoromethyl)-1,3,4-thiadiazole and 2,5-bis-(methylthio)-1,3,4-thiadiazole and selectively removing the 2,5-bis- (methylthio)-1,3,4-thiadiazole by acidifying the mixture.