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7-aryl-3,9-diazabicyclo(3.3.1)non-6-ene derivatives and their use as renin inhibitors in the treatment of hypertension, cardiovascular or renal diseases

机译:7-芳基-3,9-二氮杂双环(3.3.1)非6-烯衍生物及其作为肾素抑制剂的用途,用于治疗高血压,心血管或肾脏疾病

摘要

The invention relates to novel 3,9-diazabicyclo[3.3.1]nonene derivatives of formula (I) and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors or renin.
机译:本发明涉及式(I)的新型3,9-二氮杂双环[3.3.1]壬烯衍生物和相关化合物及其在制备药物组合物中作为活性成分的用途。本发明还涉及相关方面,包括化合物的制备方法,包含一种或多种这些化合物的药物组合物,尤其是它们作为抑制剂或肾素的用途。

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