首页>
外国专利>
Methods for multiple parameter screening and evolution of cells to produce small molecules with multiple functionalities
Methods for multiple parameter screening and evolution of cells to produce small molecules with multiple functionalities
展开▼
机译:用于细胞多参数筛选和进化以产生具有多种功能的小分子的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention relates to the field of selecting cells producing compounds that fulfil at least 2 predetermined functionalities. The invention primarily focuses on methods for screening of cells for two or more functionalities related to small molecules generated by host cells with novel gene assemblies. The methods in one aspect of the invention are combined with methods for evolution of cells to acquire at least two predetermined functionalities related to small molecules. Furthermore, the invention relates to methods for generation of lead compounds that are selected for a primary function and at least one further secondary function. The methods according to the invention may in particular be used in high troughput screening.
展开▼