High expression locus vector based on ferritin heavy chain gene locus

摘要

The invention discloses the cance high-expression gene seat carrier of part based on the ferritin heavy chain locus.This carrier comprises from the far-end 5 ' flanking sequence of ferritin heavy chain locus and/or near-end 5 ' regulates sequence.This carrier comprises the insertion site of heterologous sequence, near-end 3 ' adjusting sequence and far-end 3 ' flanking sequence.Near-end 3 ' adjusting sequence and far-end 3 ' flanking sequence are randomly from the ferritin heavy chain locus.The method that the invention also discloses the carrier cell transformed and produce the heterologous protein of vector encoded.