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Improvement of the bioavailability of active substances having an amidine function in medicaments
Improvement of the bioavailability of active substances having an amidine function in medicaments
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机译:改善具有function功能的活性物质在药物中的生物利用度
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摘要
The invention relates to the use of N,N'-dihydroxyamidine (I), N,N'-dihydroxyamidine ether (II), N,N'-dihydroxyamidine diether (III), N,N'-dihydroxyamidine ester (IV), N,N'-dihydroxyamidine diester (V) or 4-hydroxy-1,2,4-oxadiazoline (VI) of the formulae cited above, wherein R represents hydrogen, an alkyl and/or aryl radical, as a substitute for an amidine function of a medicament for improving the bioavailability of the medicament.
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