Modulators of beta-2-adrenergic receptor for treating conditions characterized by disorganized vasculature

摘要

The invention provides medicaments comprising an agent, which selectively modulates 2-adrenergic receptor conformation, or receptor activity, or activation thereof. The medicaments may be used for treating diseases that are characterised by disorganized and/or abnormal vasculature, such as cancer and metastatic disease. The medicaments may also be used for promoting organized/normal branched vasculature.