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N PROTEIN FUSION PROTEINS OF A VIRUS IN THE PARAMYXOVIRIDAE-PROTEIN OF INTEREST FAMILY

机译:兴趣家族的谷氨酰胺酶蛋白中的一种病毒的N蛋白融合蛋白

摘要

The invention relates to N protein fusion proteins of interest, possibly in the form of N protein protein of interest/P protein soluble complexes, the N and P proteins being proteins of a virus in the Paramyxoviridae family. When the protein of interest is an antigen, the invention also relates to vaccine compositions and reagents of the diagnostic comprising these N protein-antigen fusion proteins or these N protein-antigen/P protein complexes. The N protein-protein of interest fusion may also be used as a 'vector' to transport therapeutic molecules of interest in the cells, such as antiviral or anticancer molecules.
机译:本发明涉及目的N蛋白融合蛋白,可能以目的N蛋白/ P蛋白可溶性复合物的形式存在,N和P蛋白是副粘病毒科中病毒的蛋白。当目的蛋白质是抗原时,本发明还涉及包含这些N蛋白质-抗原融合蛋白或这些N蛋白质-抗原/ P蛋白质复合物的疫苗组合物和诊断试剂。感兴趣的N蛋白-蛋白融合体也可以用作“载体”以在细胞中转运感兴趣的治疗性分子,例如抗病毒或抗癌分子。

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