LIGHT-INDUCIBLE AND RHYTHMICALLY EXPRESSED GENES AND METHOD FOR SCREENING SUBSTANCES THAT AFFECT AN INTERNAL CLOCK SYSTEM

摘要

A method for screening a substance that affect an internal clock system in an organism, comprising the detection of the expression level of a gene exhibiting a Iight- inducible and rhythmic expression in a circadian manner, which is typically expressed in the suprachiasmatic nucleus of mammalian, such as for example, Dusp4, Snk, S I c39a6 or Nnat.