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SYNTHETIC LDL AS TARGETED DRUG DELIVERY VEHICLE

机译:合成LDL作为有针对性的药物交付车辆

摘要

The present invention provides a synthetic LDL nanoparticle comprising a lipid moiety and a synthetic chimeric peptide so s to be capable of binding the LDL receptor. The synthetic LDL nanoparticle of the present invention is capable of c incorporating and targeting therapeutics for diseases associated with the expression of the LDL receptor. The invention further provides methods of using such synthetic LDL nanoparticles.
机译:本发明提供了包含脂质部分和合成嵌合肽的合成LDL纳米颗粒,从而能够结合LDL受体。本发明的合成LDL纳米颗粒能够掺入并靶向与LDL受体表达有关的疾病的治疗剂。本发明进一步提供了使用这种合成的LDL纳米颗粒的方法。

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