TOPICAL APPLICATION OF FSH, LH, TSH OR CG TO THE CERVIX

摘要

A method of inducing relaxation of the cervix of a female mammal, the method comprising administering at least one pharmaceutical agent selected from follicle stimulating hormone or a beta-subunit thereof, luteinizing hormone or a beta- subunit thereof, thyroid stimulating hormone or a beta-subunit thereof, and chorionic gonadotrophin or a beta-subunit thereof, topically to the cervix of the mammal. The method can be used to facilitate artificial insemination of the female mammal. Also provided are medicinal formulations containing one or more of these hormones formulated as topical preparations or vaginal suppositories. A device comprising a sponge or foam impregnated with the hormone or hormone mixture is also provided.