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HIV PEPTIDES FROM TAT,REV AND WEF CONSERVED REGIONS AND THEIR APPLICATION AS E.GVACINE COMPNENTS
HIV PEPTIDES FROM TAT,REV AND WEF CONSERVED REGIONS AND THEIR APPLICATION AS E.GVACINE COMPNENTS
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机译:来自TAT,REV和WEF保守地区的HIV肽及其作为电子疫苗成分的应用
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摘要
The present invention comprises novel and modified peptides capable of inducing a HIV-1 specific immune response without antagonizing the cytotoxic T-cell activity in order to achieve an effective prophylactic and therapeutic vaccine against HIV. The peptides are based on conserved regions of HIV Tat and Rev, regulatory proteins and Nef, auxiliary proteins. Antigens in free- or carrier-bound form comprising at least one of the said peptides, vaccine compositions containing at least one of the antigens, immunoassay kits and a method of detecting antibodies induced by HIV or HIV specific peptides using such antigens, are described.
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