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Microchannel array component, microchannel array for recovering biomolecules, and method for recovering biomolecules

机译:微通道阵列组件,用于回收生物分子的微通道阵列以及回收生物分子的方法

摘要

Various types of biomolecules as the objects of recovery included in a sample solution in minute amounts are separated in accordance with their affinity for various types of probe molecules and readily recovered. A sample solution 8 including biomolecules 7 as the objects of recovery are poured into a microchannel array 6. After the biomolecules 7 are bound to probe molecules which are fixed on the wall of a microchannel in the form of spots and which have a high affinity for the biomolecules 7, a second substrate having periodic protrusions is removed from the microchannel array 6. A portion of the microchannel array 6 that includes a spot in which the probe molecules that are bound to the biomolecules 7, which are the objects of recovery for the first substrate, are fixed is cut with a sharp cutting knife, for example, thereby obtaining a piece that retains on the surface the probe molecules that are bound to the biomolecules 7.
机译:根据它们对各种探针分子的亲和力,将微量的各种生物分子作为样品溶液中所包含的回收对象进行分离,并易于回收。将包括作为回收对象的生物分子7的样品溶液8倒入微通道阵列6中。将生物分子7结合到探针上后,这些探针分子以斑点的形式固定在微通道壁上,并且对分子具有很高的亲和力。然后,从微通道阵列6中去除具有周期性突起的第二基质。微通道阵列6的一部分包括一个斑点,在该斑点中结合有生物分子7的探针分子被回收。例如,用锋利的切割刀切割固定的第一基板,从而获得一块将与生物分子7结合的探针分子保留在表面上的片。

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