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Substrates and methods for assaying deubiquitinating enzymes activity
Substrates and methods for assaying deubiquitinating enzymes activity
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机译:用于测定去泛素化酶活性的底物和方法
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摘要
The invention relates to substrates and methods suitable for assaying deubiquitinating enzyme activity, and in particular for screening inhibitors of enzymes involved in removal of mono or poly-ubiquitin chains from a target protein as well as inhibitors of ubiquitin precursors. Such inhibitors may have utility in the treatment of disease states associated with ubiquitin processing as well as proteolysis.
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