NON-HUMAN ANIMAL MODEL WHICH CAN BE USED TO IDENTIFY PHARMACEUTICAL COMPOUNDS WHICH REGULATE THE HEDGEHOG PATHWAY, AND APPLICATIONS THEREOF

摘要

The present invention describes a non-human animal model which can be used to identify pharmaceutical compounds which regulate the formation, diffusion and reception of lipoproteic particles using hedgehog. These pharmaceutical compounds which regulate the formation, diffusion and reception of lipoproteic particles using hedgehog can be used to make a medicament for treating human diseases, preferably cancer.