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AN IMPROVED MOLECULAR DIAGNOSTIC AND COMPUTERIZED DECISION SUPPORT SYSTEM INCORPORATING BIOINFORMATIC SOFTWARE FOR SELECTING THE OPTIMUM TREATMENT FOR HUMAN CANCER
AN IMPROVED MOLECULAR DIAGNOSTIC AND COMPUTERIZED DECISION SUPPORT SYSTEM INCORPORATING BIOINFORMATIC SOFTWARE FOR SELECTING THE OPTIMUM TREATMENT FOR HUMAN CANCER
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机译:改进的分子诊断和计算机决策支持系统,结合生物信息软件以选择最适合人类的治疗方法
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摘要
A computerized decision support system and method for predicting which of one or more drugs suitable to treat a cancerous condition in a patient are the optimum drug(s), where such selection is based upon the particular patient' s genotype. A PCR kit and/or a gene chip detects multiple genes, expressions and/or mutations associated with a particular cancer using a sample of the patient's tissue or blood. A detector accepts the gene chip and analyzes the patient's genotype; and a computerized system utilizing a gene expression cutoff point uses a database which associates patient genotypes and the efficacy and toxicity of various anti-cancer drugs used in treating patients with a particular cancerous condition connected to the detector to correlate the output of the detector to the database to provide a definitive recommendation as to which drug or drugs are optimum for treating the patient's cancer.
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