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METHOD FOR DETERMINING EFFECT OF CISPLATIN ADMINISTRATION AND KIT FOR DETERMINING EFFECT OF CISPLATIN ADMINISTRATION

机译:确定西沙丁胺管理作用的方法和试剂盒测定西沙丁胺管理作用的试剂盒

摘要

It is determined whether or not cisplatin administration has a therapeutic effect with high accuracy and specificity. A method for determining an effect of cisplatin administration comprises a step a in which the expression of at least one gene selected from the group consisting of PDE3B (phosphodiesterase 3B) gene, PDGFC (platelet derived growth factor C) gene, PKD2 (polycystic kidney disease 2) gene, NRG1 (neuregulin 1) gene and LUM (lumican) gene in a biological sample collected from a subject to be diagnosed is measured, and a step b in which an effect of cisplatin administration is determined based on the expression level of the gene obtained as the measurement result.
机译:确定顺铂给药是否具有高精度和特异性的治疗效果。确定顺铂给药作用的方法包括步骤a,其中表达选自PDE3B(磷酸二酯酶3B)基因,PDGFC(血小板衍生生长因子C)基因,PKD2(多囊性肾病)的至少一种基因2)测量从待诊断的受试者收集的生物样品中的基因,NRG1(神经调节蛋白1)基因和LUM(lumican)基因,并在步骤b中根据顺铂的表达水平确定顺铂给药的效果。获得的基因作为测量结果。

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