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LONG CHAIN N-ALKYL COMPOUNDS AND OXA-DERIVATIVES THEREOF AND USE AS ANTIVIRAL COMPOSITIONS

机译:长链N-烷基化合物及其氧杂衍生物及其用作抗病毒组合物的用途

摘要

Long chain N-alkyl amino and imino compounds, oxa-substituted derivatives thereof, and pharmaceutical compositions including such compounds are described. The long chain N-alkyl group is a C8-C16 alkyl group. The long chain N-alkyl compounds and oxa-substituted derivatives thereof can be used in the treatment of viral infections, in particular hepatitis B virus or hepatitis C virus, in a cell or an individual. For example, the long chain N-alkyl compounds or oxa-substituted derivatives thereof can be derived from piperidines, pyrrolidines, phenylamines, pyridines, pyrroles, or amino acids.
机译:描述了长链N-烷基氨基和亚氨基化合物,其氧杂取代的衍生物以及包括此类化合物的药物组合物。长链N-烷基为C8-C16烷基。长链N-烷基化合物及其氧杂取代的衍生物可用于治疗细胞或个体中的病毒感染,特别是乙型肝炎病毒或丙型肝炎病毒。例如,长链N-烷基化合物或其氧杂取代的衍生物可以衍生自哌啶,吡咯烷,苯胺,吡啶,吡咯或氨基酸。

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