A METHOD OF SURFACE PLASMON RESONANCE (SPR) TECHNOLOGY TO DETECT GENOMIC ABERRATIONS IN PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA

摘要

The present invention discloses using SPR technology to detect CLL related genomic aberrations in peripheral blood samples. An efficient formula to make a mixed SAM that can greatly enhance the immobilization ability of the metal surface in SPR based techniques, which is good for the immobilization of DNA markers used for the identification of CLL related genomic aberrations in peripheral blood samples is also disclosed.