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GAS-FILLED MICROVESICLES WITH TARGETING LIGAND IN RESPECT OF FC-REGION OF AN ANTIBODY OR THERAPEUTIC AGENT
GAS-FILLED MICROVESICLES WITH TARGETING LIGAND IN RESPECT OF FC-REGION OF AN ANTIBODY OR THERAPEUTIC AGENT
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机译:与抗体或治疗剂的FC区有关的具有靶向配体的充气微囊
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摘要
Gas-filled microvesicles comprising a boundary envelope containing a gas, wherein said microvesicles comprise: - a first component, bound to said envelope, having binding affinity for an Fc- region of an antibody; and - a second component comprising a Fc-region of an antibody, bound to said first component through said Fc-region, said second component comprising a targeting ligand or a therapeutic agent. Aqueous suspensions of said microvesicles are particularly useful in contrast enhanced ultrasound imaging.
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