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PROCESS FOR DETECTING HELICOBACTER PYLORI USING ALIPHATIC AMIDES

机译:用脂肪酰胺检测幽门螺杆菌的方法

摘要

The present invention provides a process for detecting Helicobacter pylori using aliphatic amides in which the referred amides are converted into their corresponding acids, when in contact with the bacterium. These acids are volatile or semi-volatile compounds and can be detected in the vapor phase by means of common chromatography techniques. Propionamide or butyramide can be used as amides, forming, respectively, the propionic and butyric acids. Any other non-toxic aliphatic amide can be used. The amides in use can be orally administrated as pills or as a diluted aqueous solution by both genders, any race and age, independently of the coexistence of pathologies associated or not with this bacterium. The invention is used in the development of a new non-invasive process for the detection of H. pylori in the stomach by means of analyzing exhaled air, and can be implemented in the medical and pharmaceutical industry.
机译:本发明提供了一种使用脂肪族酰胺检测幽门螺杆菌的方法,其中当与细菌接触时,所述的酰胺被转化为它们相应的酸。这些酸是挥发性或半挥发性化合物,可以通过常规色谱技术在气相中进行检测。丙酰胺或丁酰胺可以用作酰胺,分别形成丙酸和丁酸。可以使用任何其他无毒的脂族酰胺。所用酰胺可按丸剂或稀释水溶液的形式按性别,任何种族和年龄进行口服给药,而与该细菌相关的病理学是否共存无关。本发明用于通过分析呼出空气来检测胃中幽门螺杆菌的新的非侵入性方法的开发,并且可以在医学和制药工业中实施。

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