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METHODS FOR A GLOBAL ASSAY OF COAGULATION AND FIBRINOLYSIS

机译:凝血和纤溶的全球评估方法

摘要

The present disclosure concerns methods of analyzing both clot formation and fibrinolysis in a sample, preferably simultaneously. In certain embodiments, the methods may comprise adding a small amount of at least one activator of coagulation and at least one activator of fibrinolysis to a sample and analyzing the sample for kinetic parameters related to clot formation and fibrinolysis. In another embodiment, the methods may comprise analyzing a sample from a subject for clot formation and fibrinolysis and detecting or diagnosing a disease or condition and/or applying information obtained from analyzing clot formation and fibrinolysis to determine a treatment for a medical condition of the subject.
机译:本公开涉及优选同时分析样品中的凝块形成和纤维蛋白溶解的方法。在某些实施方案中,该方法可以包括向样品添加少量的至少一种凝血活化剂和至少一种纤维蛋白溶解活化剂,以及分析样品中与血块形成和纤维蛋白溶解有关的动力学参数。在另一个实施方案中,该方法可以包括分析来自受试者的样品的血块形成和纤维蛋白溶解和检测或诊断疾病或病状和/或应用从分析血块形成和纤维蛋白溶解中获得的信息来确定受试者的医学状况的治疗方法。 。

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