A CELL-BASED PLATFORM FOR HIGH THROUGHPUT SCREENING

摘要

The present invention relates to an apparatus for testing multiple sample compounds for their biological effect comprising a porous block (1) having substantially planar top (3) and bottom surfaces (5) . The top surface (3) comprises a plurality of cell adhesive regions (7) and cell dis- adhesive regions (9) and the bottom surface (5) provides multiple sites (11) to load the sample compounds. These sites are located opposite from the cell adhesive regions on the top surface of the porous block. In certain embodiments, the invention further comprises at least one dissolvable layer (13) which provides multiple sites to load the sample compounds .