ESTIMATION OF A MEASURE OF CONTRAST AGENT CONCENTRATION USING AN ANALYTICAL MATHEMATICAL MODEL

摘要

A vascular input function, to estimate a measure of contrast agent concentration, which is decomposed into a function component representing the bolus of contrast-enhancing agent and a function component representing equilibration of the bolus by leakage from the circulatory system of the subject in to other parts of the body of the subject (referred to as the 'body transfer function'). Restricting the components to suitable analytical (e.g. algebraic) mathematical functions ensures that the calculations can be carried out analytically.