wherein n is 2 or 3; andR1 representsor pharmaceutically acceptable salts thereof, to novel processes for preparing the same, to use thereof as anti-allergic, anti-anaphylactic, anti-inflammatory and hypolipidemic agents as well as to a pharmaceutical composition comprising the indicated compounds in an efficient amount and to a method for treating allergic and inflammatory diseases and lipid metabolism disorders: bronchial asthma, allergic rhinitis, pollinoses, seasonal and year-round rhinitis, allergic pneumonitis, atopic dermatitis, psoriasis, urticaria, allergic (including anaphylactic) reactions to insect stings and medicaments, cold allergy, allergic conjunctivitis, atherosclerosis, obesity, ischemic heart and cerebral disease, myocardial infarction and stroke."/>
N-ACYLIC AMINOACID DERIVATIVES. METHOD FOR THE PRODUCTION THEREOF, PHARMACOLOGICAL COMPOSITION AND THE USE IN THE FORM OF ANTI-ALLERGIC, ANTI-INFLAMMATORY AND HYPOLIPIDEMIC AGENTS
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N-ACYLIC AMINOACID DERIVATIVES. METHOD FOR THE PRODUCTION THEREOF, PHARMACOLOGICAL COMPOSITION AND THE USE IN THE FORM OF ANTI-ALLERGIC, ANTI-INFLAMMATORY AND HYPOLIPIDEMIC AGENTS
N-ACYLIC AMINOACID DERIVATIVES. METHOD FOR THE PRODUCTION THEREOF, PHARMACOLOGICAL COMPOSITION AND THE USE IN THE FORM OF ANTI-ALLERGIC, ANTI-INFLAMMATORY AND HYPOLIPIDEMIC AGENTS
The present invention relates to N-acyl derivatives of amino acids and pharmaceutically acceptable salts thereofwherein n is 2 or 3; andR1 representsor pharmaceutically acceptable salts thereof, to novel processes for preparing the same, to use thereof as anti-allergic, anti-anaphylactic, anti-inflammatory and hypolipidemic agents as well as to a pharmaceutical composition comprising the indicated compounds in an efficient amount and to a method for treating allergic and inflammatory diseases and lipid metabolism disorders: bronchial asthma, allergic rhinitis, pollinoses, seasonal and year-round rhinitis, allergic pneumonitis, atopic dermatitis, psoriasis, urticaria, allergic (including anaphylactic) reactions to insect stings and medicaments, cold allergy, allergic conjunctivitis, atherosclerosis, obesity, ischemic heart and cerebral disease, myocardial infarction and stroke.
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机译：本发明涉及氨基酸的N-酰基衍生物及其药学上可接受的盐 <图像文件=“ IMGA0001.GIF” he =“ 23” imgContent =“ chem” imgFormat =“ GIF” wi =“ 86” /> 其中n为2或3;和R 1 代表 <图像文件=“ IMGA0002.GIF” he =“ 30” imgContent =“ chem” imgFormat =“ GIF” wi =“ 99” /> 或其药学上可接受的盐，制备它们的新方法，将其用作抗过敏，抗过敏，抗炎和降血脂药，以及包含有效量的所示化合物的药物组合物，以及变应性和炎症性疾病和脂质代谢异常的治疗方法：支气管哮喘，变应性鼻炎，花粉症，季节性和全年性鼻炎，变应性肺炎，特应性皮炎，牛皮癣，荨麻疹，对昆虫st和药物的过敏（包括过敏性）反应，感冒过敏，过敏性结膜炎，动脉粥样硬化，肥胖，缺血性心脑疾病，心肌梗塞和中风。
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