USE OF CHOLINE TO PREVENT THROMBOSIS ASSOCIATED WITH TOTAL PARENTERAL NUTRITION

摘要

Choline deficiency is a risk factor for the development of thrombosis in patients with intestinal failure that require total parenteral nutrition. There is provided a method of preventing thrombosis, preferably venous thrombosis, comprising administering to a patient receiving TPN a nutrient solution comprising choline. Also provided is a method of diagnosing a risk for thrombosis comprising taking a sample from a patient and detecting the level of plasma-free choline.