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Prolonged release microspheres for injection delivery and preparation method
Prolonged release microspheres for injection delivery and preparation method
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机译:注射剂用缓释微球及其制备方法
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摘要
The subject of the present invention is microspheres intended to be administered by injection, comprising a protein active ingredient and an agent coating the active ingredient intended to prolong its release, free of any trace of organic solvent and obtainable according to a coating method involving bringing the active ingredient and the coating agent into contact, with stirring, in a supercritical fluid, the said coating agent being soluble in the supercritical fluid. The protein active ingredient is not denatured.
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