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EXPRESSION VECTOR HAVING PROMOTER SEQUENCE OF VASA HOMOLOGUE GENE DERIVED FROM MAMMAL AND USE THEREOF
EXPRESSION VECTOR HAVING PROMOTER SEQUENCE OF VASA HOMOLOGUE GENE DERIVED FROM MAMMAL AND USE THEREOF
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机译:具有哺乳动物源VASA同源基因启动子序列的表达载体及其应用。
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摘要
Disclosed is a method for screening a cell capable of differentiating into a germ cell in a simple manner by utilizing the expression of a marker gene as an indicator, which does not need any complicated operations such as homologous recombination. A method for producing a germ cell comprising the step of collecting a cell capable of differentiating into a germ cell from a transgenic non-human mammal having a recombinant expression vector introduced therein utilizing the expression of a marker gene as an indicator, the recombinant expression vector having the marker gene integrated therein such a manner that the marker gene is placed under the regulation of a promoter sequence of a Vasa homologue gene derived from a mammal.
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