AQUAPORINS WATER CHANNELS AND VAGINAL LUBRICATION FOR MODULATING THE SAME

摘要

Water channel proteins aquaporins which participate in water movement are provided to promote secretion of vaginal lubricating liquid. A vaginal lubricant is also provided to promote secretion of vaginal lubricating liquid by modulating expressions of the water channel proteins. A vaginal lubricant for promoting secretion of vaginal lubricating liquid modulates the expressions of water channel proteins aquaporins including aquaporin-1, aquaporin-2, aquaporin-3 and aquaporin-8, wherein the aquaporin-1 is expressed in capillary blood vessel, venule and smooth muscle in vaginal tissue, and the aquaporin-2 and aquaporin-3 are expressed in vaginal tissue epithelial cytoplasm.