N-Heterocyclylbenzene or Pyridine Sulphonamides as Antithrombotic Agents and Anticoagulants

摘要

Compounds of formula [I]in which:W may represent a -(CH2)2-, -(CH2)3-, -CH2-C=C- or -CH2-CH=CH- group,R2 may in particular represent a piperidyl group, an optionally substituted 1,2,3,6-tetrahydropyridyl group, a hexahydro-1H-azepinyl group, an optionally substituted piperazinyl group or a morpholinyl group,R3 may in particular represent a group -COR1,A may in particular represent an optionally substituted phenyl group, a heterocycle or a cyclopentyl group, andB may in particular represent a pyridyl group, an aminopyrazinyl group, an aminopyridazinyl group, a pyrimidinyl group optionally substituted with an amino group, piperidyl group or an aminopyridyl group optionally substituted on the pyridine with a (C1-C4)alkyl or (C1-C4)alkoxy group, the amino group possibly also being substituted with a (C1-C4)alkyl group,their preparation and their therapeutic application.