Processes for the preparation of a piglet for xeno-organ transplantation

摘要

invention 3-7 -week-old pigs in the 300 ~ 500 cGY of radiation absorbed dose to the whole body irradiation comprising the step of , for a method of producing pig Xenotransplantation and provides a pig for Xenotransplantation obtained by the above production method . The present invention also do not have a significant change in the blood level of the blood cells for survival , such as red blood cell production method according to the heterogeneous and provides the extraction from pig organs for transplant . ; This invention standing for white blood cells and CD4 + T and CD8 + T cells was only selectively reduce Xenotransplantation immune cells , such as a pig can be produced . Thus , pigs obtained by the process of the present invention may provide long-term , which may be implanted in a mammal such as a human .