HIGH MOLECULAR- TITANIA-HYDROXYAPATITE COMPOSITE NANOFIBERS AND ITS MANUFACTURING METHOD AND, TITANIA-HYDROXYAPATITE COMPOSITE NANOFIBERS AND ITS MANUFACTURING METHOD

摘要

A titania-hydroxyapatite composite nanofiber is provided to expand applicabilities as a bone substituting material, and to improve biocompatibility and bio-friendliness. A preparation of titania-hydroxyapatite composite nanofiber comprises the steps of: dissolving a polyvinyl group polymer in 2-methoxyethanol to obtain a 8-13wt% concentration polymer sol; mixing Titanium(IV) isopropoxide (TIP), 2-methoxyethanol, and acetic acid at the same volume ratio to obtain a ceramic precursor sol; mixing the polymer sol and the precursor sol at a ratio of 4-6:6-4 and stirring the mixture over a period of 10-14 hours to obtain a polymer ceramic precursor sol; adding the polymer ceramic precursor sol to a hydroxyapatite(HA) sol at a volume ratio of 4-6 and stirring the mixture over a period of 20-28 hours to obtain a polymer/titania/HA sol; electro-spinning the resulting sol to obtain the target nanofiber. Preferably, calcination is carried out at 600deg.C for 3 hours for titania and HA to have a ceramic crystalline structure.