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TREATMENT BY HEMCITABIN AND AN EPIDERMAL GROWTH FACTOR (EGFR) RECEPTOR INHIBITOR

机译:HEMCITABIN和表皮生长因子(EGFR)受体抑制剂的治疗

摘要

1. A pharmaceutical composition, primarily intended for use in the treatment of cancer, comprising an epidermal growth factor receptor kinase inhibitor (EGFR) and gemcitabine in a pharmaceutically acceptable carrier. The pharmaceutical composition according to claim 1, wherein the EGFR receptor kinase inhibitor is erlotinib. The pharmaceutical composition according to claim 2, wherein erlotinib in the composition is used in the form of hydrochloride. The pharmaceutical composition according to claim 2 or 3, further comprising one or more other antitumor agents. A method for producing a medicament for the treatment of tumors or tumor metastases, which comprises an EGFR receptor kinase inhibitor and gemcitabine. 6. The method of claim 5, wherein the medicament is for treating cancer. The method of claim 5 or 6, wherein the EGFR receptor kinase inhibitor and gemcitabine are contained in the same composition. The method of claim 5 or 6, wherein the EGFR receptor kinase inhibitor and gemcitabine are contained in various compositions. The method of claim 5, wherein the EGFR receptor kinase inhibitor and gemcitabine are intended to be administered to a patient in the same manner. The method of claim 9, wherein the EGFR receptor kinase inhibitor and gemcitabine are intended to be administered to a patient in various ways. The method of claim 10, wherein erlotinib is used as an EGFR receptor kinase inhibitor. The method of claim 11, wherein erlotinib is intended for administration to a patient in a parenteral or oral manner. The method of claim 10, wherein gemcitabine is intended for administration to a patient by a parenteral route. The method of claim 5, further comprising
机译:1.一种主要用于治疗癌症的药物组合物,其在可药用载体中包含表皮生长因子受体激酶抑制剂(EGFR)和吉西他滨。 2.根据权利要求1所述的药物组合物,其中,所述EGFR受体激酶抑制剂是厄洛替尼。 3.根据权利要求2所述的药物组合物,其中,所述组合物中的厄洛替尼以盐酸盐的形式使用。 4.根据权利要求2或3所述的药物组合物,其进一步包含一种或多种其他抗肿瘤剂。一种用于生产用于治疗肿瘤或肿瘤转移的药物的方法,其包含EGFR受体激酶抑制剂和吉西他滨。 6.根据权利要求5所述的方法,其中所述药物用于治疗癌症。 7.根据权利要求5或6所述的方法,其中所述EGFR受体激酶抑制剂和吉西他滨被包含在相同的组合物中。 7.根据权利要求5或6所述的方法,其中所述EGFR受体激酶抑制剂和吉西他滨包含在各种组合物中。 6.根据权利要求5所述的方法,其中所述EGFR受体激酶抑制剂和吉西他滨旨在以相同方式施用于患者。 11.根据权利要求9所述的方法,其中所述EGFR受体激酶抑制剂和吉西他滨旨在以各种方式施用于患者。 11.权利要求10的方法,其中厄洛替尼用作EGFR受体激酶抑制剂。权利要求11的方法,其中厄洛替尼旨在以肠胃外或口服方式给予患者。 11.根据权利要求10所述的方法,其中吉西他滨旨在通过肠胃外途径向患者给药。 6.根据权利要求5所述的方法,进一步包括

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