METHOD OF APPLICATION OF COMPOSITIONS CONTAINING HEAT-SHOCK PROTEINS OR ALPHA-2-MACROGLOBULIN FOR TREATMENT OF CANCER AND INFECTIOUS DISEASES

摘要

FIELD: medicine.;SUBSTANCE: composition containing the population of complexes of one or more heat-shock proteins (HSP) and antigenic peptides (AgP) are administered to the patient; in addition, at least one therapeutic agent, which doesn't contain the HSP is administered, to prevent or treat cancer. The population of complexes is received by use of the method, which provides the protein hydrolysis by one or more proteases and its decomposition by one or more non-enzyme methods, with obtaining the AgP population and formation of HSP with AgP complex. The protein agent is obtained from the cells with the same cancer antigenicity that should be treated or prevented in subject, and contains at least 50% or 50 different proteins of original antigen cells or cell fractions. The kit includes the containers with the described composition and treatment agent.;EFFECT: invention provides increased immune response in cancer and improved of therapeutic effect with reduced side action of treatment agent when used in combination with composition.;30 cl, 1 tbl