METHOD OF AGE-SPECIFIC CATARACT MODELLING

摘要

FIELD: medicine.;SUBSTANCE: invention concerns ophthalmology and is intended for cataract modelling for the purpose of subsequent analysis of anticataract efficiency of medical products. Rats aged 20-23 days are exposed to ultra-violet irradiation. Total UF irradiation is performed at wavelength 313 nm within 10 months for 16 minutes once a day every second day, irradiation power is 23.7 J/s·m². Method invokes cataract close to age-specific cataract with activation of photooxidation and aggregation of water-soluble fibres, and cumulation of photolysis products serving as pathogenetic factor of age-specific cataract development.;EFFECT: invokes cataract close to age-specific cataract with activation of photooxidation and aggregation of water-soluble fibres, and cumulation of photolysis products.;3 dwg, 1 ex