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Electrically active combinatorial-chemical (electrically-active combinatorial-chemical; eacc) chip for biochemical analyte determination
Electrically active combinatorial-chemical (electrically-active combinatorial-chemical; eacc) chip for biochemical analyte determination
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机译:用于生化分析物测定的电活性组合化学(EAC)芯片
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摘要
Apparatus and methods are disclosed for electrically active combinatorial-chemical (EACC) chips for biochemical analyte detection. An apparatus includes a substrate that has an array of regions defining multiple cells, wherein each of the cells includes a reaction cavity that contains multiple functional binding groups. A method of detecting an analyte providing the reaction cavity between a source and a drain or a pair of electrodes, applying a voltage and monitoring a parameter indicative of an analyte characteristic. A process of fabricating an EACC include bonding an analyte to the multiple functional binding groups of each reaction cavity, and forming an analyte sensing structure including the substrate.
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