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Analysis system based on porous material for highly parallel individual cell detection

机译:基于多孔材料的分析系统,用于高度平行的单个细胞检测

摘要

The present invention relates to analytical systems, based on porous material (1), for example, silicon, for highly parallel individual cell detection. In particular, the present invention relates to a porous silicon (1) having a multiplicity of continuous channels (2) and to the use thereof at least for cell separation, for cell lysis and purification of target molecules, for amplification of nucleic acid molecules or for detection of desired target molecules. The present invention also relates to an analytical method with the use of porous silicon (1). On the inner walls of the channels (2) are monoclonal antibodies (11) for cell separation and immobilized capture molecules (12) mounted for cell lysis and purification.
机译:本发明涉及基于多孔材料(1)例如硅的用于高度平行的单个细胞检测的分析系统。特别地,本发明涉及具有多个连续通道(2)的多孔硅(1),并涉及其至少用于细胞分离,细胞裂解和靶分子纯化,核酸分子扩增或纯化的用途。用于检测所需的目标分子。本发明还涉及使用多孔硅(1)的分析方法。在通道(2)的内壁上是用于细胞分离的单克隆抗体(11)和安装用于细胞裂解和纯化的固定捕获分子(12)。

著录项

  • 公开/公告号DE102006033875A1

    专利类型

  • 公开/公告日2008-01-31

    原文格式PDF

  • 申请/专利权人

    申请/专利号DE20061033875

  • 发明设计人

    申请日2006-07-21

  • 分类号C12M1/34;C12Q1/68;G01N33/50;

  • 国家 DE

  • 入库时间 2022-08-21 19:49:50

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