首页> 外国专利> New, well tolerated metal chelates, for use as radiodiagnostic, radiotherapeutic or NMR and X-ray diagnostic agents, contain chelator and perfluorinated polyethylene glycol residues

New, well tolerated metal chelates, for use as radiodiagnostic, radiotherapeutic or NMR and X-ray diagnostic agents, contain chelator and perfluorinated polyethylene glycol residues

机译:用作放射诊断,放射治疗或NMR和X射线诊断剂的耐受性良好的新型金属螯合物含有螯合剂和全氟聚乙二醇残基

摘要

New metal chelates (I) (optionally in salt form) contain (a) perfluorinated polyethylene glycol (PEG) residue(s), (b) chelator residue(s) and (c) at least one equivalent of metal(s) of atomic number 21-29, 31-33, 37-39, 42-44, 49 or 57-83. An independent claim is included for new metal-free chelating agent intermediates (II), containing the components (a) and (b). ACTIVITY : Cytostatic. MECHANISM OF ACTION : Radiotherapy.
机译:新的金属螯合物(I)(可选为盐形式)包含(a)全氟聚乙二醇(PEG)残基,(b)螯合剂残基和(c)至少一当量的原子金属21-29、31-33、37-39、42-44、49或57-83号。对于包含组分(a)和(b)的新型无金属螯合剂中间体(II),包括独立的权利要求。活动:细胞静息。作用机理:放射疗法。

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