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Human monoclonal antibody to Ep-CAM and its use in cancer therapy
Human monoclonal antibody to Ep-CAM and its use in cancer therapy
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机译:人抗Ep-CAM单克隆抗体及其在癌症治疗中的应用
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摘要
The invention provides a method for selecting at least one member from a library of proteinaceous molecules comprising providing at least one cell and/or a functional equivalent thereof, with at least part of said library under conditions that allow binding of any such member to an epitope in and/or on said cells and/or said functional equivalent thereof, removing unbound proteinaceous molecules and selecting said at least one member, wherein said library comprises at least one mutant of a proteinaceous molecule capable of binding to said epitope. IMAGE
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