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A RELATIONSHIP AND ANTITUM ORDER THAT MAKES THE ANTITUM IMPACT

机译:产生反作用力的关系和反作用令

摘要

The present invention provides an antitumor effect potentiator for enhancing antitumor activity of an antitumor agent comprising tegafur in a therapeutically effective amount, gimeracil in an amount effective for enhancing an antitumor effect, and oteracil potassium in an amount effective for inhibiting a side effect. The antitumor effect potentiator comprising at least one member selected from the group consisting of folinic acid and pharmacologically acceptable salts thereof. The present invention also provides a method for enhancing an antitumor effect of an antitumor agent comprising the step of administering to a patient the aforementioned antitumor effect potentiator; and a method for cancer treatment comprising the step of administering to a patient the aforementioned antitumor agent.
机译:本发明提供了用于增强抗肿瘤剂的抗肿瘤活性的抗肿瘤效果增强剂,其包含治疗有效量的替加氟,以有效增强抗肿瘤作用的量的吉美拉西和以抑制抑制副作用的有效量的奥特拉西钾。该抗肿瘤作用增强剂包含至少一种选自亚叶酸及其药理学上可接受的盐的成员。本发明还提供了一种增强抗肿瘤剂抗肿瘤作用的方法,该方法包括以下步骤:向患者施用上述抗肿瘤作用增强剂。以及用于癌症治疗的方法,其包括向患者施用上述抗肿瘤剂的步骤。

著录项

  • 公开/公告号DE602004016636D1

    专利类型

  • 公开/公告日2008-10-30

    原文格式PDF

  • 申请/专利权人 TAIHO PHARMACEUTICAL CO. LTD.;

    申请/专利号DE20046016636T

  • 发明设计人 UCHIDA JUNJI;SHUDO KOYO;

    申请日2004-03-11

  • 分类号A61K31/53;A61K31/519;C07D239/54;C07D475/04;C07D487/04;

  • 国家 DE

  • 入库时间 2022-08-21 19:48:11

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